Lane Roanoke is only fifteen years old when her mother commits suicide. With nowhere else to go, Lane moves in with her maternal grandparents and cousin Allegra on their farm in rural Kansas. Knowing little about her extended family, Lane is excited at the prospects of having a family to care for her. Lane quickly embraces life as a Roanoke, but it isn't long before Lane realizes that the Roanoke family has a dark secret to keep; one that sends her running far away from the small farming town in Kansas.
Years later, Lane still figuring out her life, receives a phone call from her grandfather telling Lane that her cousin Allegra has gone missing. Has Allegra run away like the Roanoke girls before her or is it something more sinister? Unable to get Allegra out of her mind, Lane returns to help ease the guilt she feels after having left Allegra behind. While Lane's homecoming means a chance for second chances, it also means that she must face the Roanoke secret that made her run.
Weaving between now and then, The Roanoke Girls is filled with twists and turns, exploring the lengths at which families will go to keep their deep, dark secrets and the love that they share.